It's not 'better'.
I want to say there are may good clients, it's a very good idea to run more than one single client on your computer. Yep, each client has it strength somewhere else: Some are good for music, some for movies, some for ISOs, some are good if you're a bloddy newbie and just wanna click'n'go (Morpheus and Xolox I guess)... and some if you like spyware.
Just a lamers two cents