I dont see why you couldn't, just as long as you have enough disk space....
The program I use is dvdsanta and it lets you enque files, it then converts them and then burns them all in very easy steps...
Nero would more than likely do this as well, but I haven't use the program so I cant be sure...

There is a demo version of dvdsanta you can try this is the link, have a look and see if you like it....

http://www.dvdsanta.com