Try deleting it in safe mode first, the link below tells you how.
http://www.pchell.com/support/safemode.shtml
Did you do an online scan here (they only work using IE)..
http://housecall.trendmicro.com/
or here..
http://www.bitdefender.com/ (choose online scan - bottom left)
If you're still having problems, visit Norbies World for help. Follow the instructions there and read a few examples of how he helps, so you know what to expect before you post
http://www.norbiesworld.co.uk/computerhelp