I have heard of people having problems when they try to share from an external drive. I would avoid this if possible. Try a search to get more info.
How are you uninstalling? You should use the Limewire uninstall option. Uninstalling via 'add/remove programs' can also cause problems.
You could also try some
fixes when Limewire isn't running properly (note the part about deleting your Limewire preferences folder).
Hope this helps