It has been discovered that McAfee, Limewire and Vista don't mix...
Many people have uninstalled McAfee altogether and connect to LW no problem, but within the last day or two we have had a member uninstall McAfee and then re-install it and all is running well...
This is the thread have a look at it, especially page 2 and 3...
http://www.gnutellaforums.com/showth...t=68271&page=2