Yeah for windows it's a little more complex. I suspect you'd need to reinstall it to that drive again. I'd recommend LW 4.12 or 4.18 at this point. Lime Wire » Download Out-Of-Date Installers for LW 4.18
Once installed, you will need to direct the shared folder to that drive as it was before.

For 4.12 check either http://www.gnutellaforums.com/340213-post427.html .. see if it works. If not, try LimeWire - DOWNLOAD at OLD VERSION.COM Please let me know if the first link 4.12 installs ok.