First try this:
http://www.gnutellaforums.com/window...tml#post183932
If that does not solve the problem, scroll back up to post #1 of that thread & see points #5 & 6 about changing compatibility mode & running as Admin.
If still problems, use this re-installation technique:
http://www.gnutellaforums.com/333278-post2.html
However rather than LW 5.1.3, use this version:
LimeWire 5.2.2 (Beta) - Lime Wire which is stable.
Warning, LW should not be uninstalled using the Add/Remove control panel. Method is via Start menu -> All Programs -> LW -> Uninstall. Else, re-installing LW will remove it at beginning of installation process.