About half way thru Apple - Support - iPod Tutorials - Downloading Music and Video shows how to name your iPod. So having a different name for each iPod might work. However Auto synching might not work for all. Manual updating probably will. That's if you are using iTunes. But as Blackhorse 70V suggested, there are 3rd party options to help load iPods.

I still could not find where I once saw about connecting more than one iPod to your computer.