Anything below 5.5.10 is safe to use. But you will probably have connection issues. You can see the
connection help pages about how to fix.
You could see the
http://www.gnutellaforums.com/gettin...-5-5-16-a.html to see what changes were made (only gives brief summary of changes.) The 5.6 betas and Pirate Edition are safe to use.