I am having the same problem. This happens to me every 3 or 4 times I start Limewire Pro 2.8.6. If I choose another directory it will continue to start successfully. Then that directory is good for 3 or 4 uses and becomes invalid. Invalid directories never become valid again. I have invalid save directories scattered across my hard drive. Uninstalling then reinstalling Limewire does not help. I just wrote tech support at Limewire about the problem.