So far, all I've had with LW in OS X (10.1.5) is that it just stops on the Loading user interface screen. I've tried restarting, uninstalling, and just about everything else I can humbly think about, nothing seems to work.
The best soution so far is real easy : I'm running LW in Classic !!!
Might sound really lo-tech, but it works just great
Hope this helps.