Let's try this step by step. Assuming you downloaded a new Limewire version and installed it on a "clean" slate (ie you chased down and trashed everything with "Limew" in the title before reinstalling), the next step is to eliminate some possible OSX problems. If you have recently downloaded an OS upgrade whether to !0.2.5 or 10.2.6, restart your machine in Safe Boot mode, ie when restarting, hold down the shift key. This will invisibly run a file check. Once that is complete, drop into Utilities and run File Permission Repairs. Now restart your machine and go through the reinstall sequence (we're actually up to 2.9.11 at present). If you still cannot launch, let us know and we'll move on to the next step.

Good luck.