I am having the same problem as bebebe.

I was on the network with Limewire working perfectly fine. Then I did two new things - I upgraded from Netscape 7.1 to 7.2 - and I upgraded DirectX to 9.0.c.

The next time I started up the system -
The icon for Limewire will not respond. I dig into the Limewire file and try again. No response. -- I upgrade to Pro 4.0.8.
Completely unistall 4.0.7. - Install 4.0.8
Still absolutely no response.

Could something between Netscapes 7.2 or more likely devilish Microsofts DirectX 9.0c have changed some essental settings for Limewire. ??