I've downloaded games like ***********. I put them on a dvd with my dvd decrypter because they are iso format. Then I download the dvd on my computer, everything is working good right now. After everything is downloaded i try to play the game but it asks me if the game is in the disc drive so i put it in and the same message comes up everytime. I need some one just to tell me why is this happening because i'm not happy about this I got limewire so I could download games but they don't work. Do I need a different disc or what just somebody give me some information on what to do.

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Instead of using a DVD, burn your ISO's on separate CD's, some of the ISO's you download from LimeWire may not be full, I had that problem with Tiger Woods. If you are getting one large ISO that will only fit on a DVD, but is normally a 2,3,4, or 5 CD installation, I'm not sure how you would sort the ISO images.

how can i play games i downloaded from my computer?

You'll find that most games won't work, they'll need a CD or code to run. Heaps of .exe. .zip & .rar files are infected. If you do decide to download those, make sure that you're using a good AV program. Keep it updated & scan files that you've downloaded before you open them.
WARNING: Viruses on the network you should be aware of